This antibody recognises CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on a 93 kDa erythrocyte membrane glycoprotein. In haemaggulation tests, BRIC203 reacts with Kp (a-b+) but not Kp (a+b-). In addition this antibody will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko Erythrocytes.
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Affinity Chromatography on Protein G
Immunogen
Human Erythrocytes. Spleen cells from immunised Balb/c were fused with cells of a myeloma cell line.
KEL
Reaktivität: Human
WB, FACS, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Immunoprecipitation. Haemagglutination. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
Tris Buffered Glycine, pH 7.8 containing 0.09 % Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
KEL
(Kell Blood Group, Metallo-Endopeptidase (KEL))
Blood Group Kell Antigen is a type II transmembrane glycoprotein. The Kell glycoprotein links to the XK membrane protein, that carries the Kx antigen via a single disulfide bond. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.Synonyms: Kell blood group glycoprotein