MCAM Antikörper

Produktnummer ABIN1112867

Der Kaninchen Polyklonal Anti-MCAM-Antikörper wurde für FACS, WB und ICC validiert. Er ist geeignet, MCAM in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für MCAM Antikörper (ABIN1112867)

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCAM Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunocytochemistry (ICC)

Produktdetails anti-MCAM Antikörper

Aufreinigung: affinity purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB (1:1000-2000), ICC (1:100-500), Flow Cyt (1:10-100). Other applications have not been tested. The optimal dilutions should be determined by end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu MCAM

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Andere Bezeichnung: CD146

Hintergrund: CD146 (cluster of differentiation 146) also known as the melanoma cell adhesion molecule (MCAM) or cell surface glycoprotein MUC18, is a 113kDa cell adhesion molecule currently used as a marker for endothelial cell lineage. In humans, the CD146 protein is encoded by the MCAM gene. 1 CD146 belongs to the immunoglobulin superfamily and expressed in all types of human endothelial cells. The regulated expression of CD146 at areas of cell-cell junction and strongly suggest involvement of CD146 as a mediator of cell-cell interaction. 2 CD146 has been seen as a marker for mesenchymal stem cells isolated from multiple adult and fetal organs, 3 and its expression may be linked to multipotency, mesenchymal stem cells with greater differentiation potential express higher levels of CD146 on the cell surface. 4