Annexin a1 Antikörper (N-Term)

Produktnummer ABIN1112715

Dieses Anti-Annexin a1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Annexin a1 in WB. Geeignet für Hund und Affe.

Kurzübersicht für Annexin a1 Antikörper (N-Term) (ABIN1112715)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reaktivität: Hund, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin a1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Annexin a1 Antikörper

Bindungsspezifität: N-Term

Spezifität: Detect endogenous level of total Annexin A1 protein.

Immunogen: A synthetic peptide (conjugated to KLH) corresponding to N-terminal residues of human Annexin A1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot (1:1000) Other applications have not been tested. The optimal dilutions should be determined by end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for 1 year. Avoid repeated freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: Annexin A1

Hintergrund: Annexin A1 / Annexin I also known as lipocortin I is a protein that in humans is encoded by the ANXA1 gene. Annexin I belongs to the annexin family of Ca2+-dependent phospholipid-binding proteins that have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Annexin I has been of interest for use as a potential anticancer drug. It inhibits the NF- kappa B signal transduction pathway, which is exploited by cancerous cells to proliferate and avoid apoptosis. ANXA1 inhibits the activation of NF-kappaB by binding to the p65 subunit.

Pathways: Hormone Transport