CD63 Antikörper (Biotin)
-
- Target Alle CD63 Antikörper anzeigen
- CD63
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD63 Antikörper ist konjugiert mit Biotin
-
Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Produktmerkmale
- Monoclonal Mouse Anti-Human CD63 BIOTIN is recommended for use in flow cytometry for identification of activated platelets.
- Klon
- TEA3-18
- Isotyp
- IgG1
- Top Product
- Discover our top product CD63 Primärantikörper
-
-
- Applikationshinweise
- It is recommended for use in flow cytometry. This reagent is effective for direct immunofluorescence staining of human tissue for flow cytometric analysis using 10 µl, 1/100, of the suggested working dilution to label 10^6 cells.
- Kommentare
-
BIOTIN (Sigma).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- The conjugate is provided in liquid form in buffer containing 1% bovine serum albumin (BSA) and 0,09% Sodium azide, pH 7.2.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
-
- Target
- CD63
- Andere Bezeichnung
- CD63 (CD63 Produkte)
- Hintergrund
- CD63 is a 53 kDa, type III lysosomal glycoprotein, expressed on activated platelets, monocytes and macrophages. CD63 contains four hydrophobic transmembrane domains with a major extracellular region of 95 amino acids between transmembrane segments 3 and 4. The COOH-terminal sequence SGYEVM functions as a lysosomal targeting sequence. This molecule is also referred highly to as LIMP, gp55,melanoma-associated antigen ME491, Pltgp40, LAMP-3 and is a member of the tetraspan transmembrane 4 superfamily (TM4SF). It is also widely expressed on surface and in the cytoplasm of various hematopoietic (monocytes, macrophages) and non-hematopoietic cells (endothelium, fibroblasts, osteoclasts, smooth muscle). Its cellular function has not been fully elucidated. Reports suggest this as a useful molecule to study platelet activation.
-