MBP Antikörper

Produktnummer ABIN1110156

Dieses Anti-MBP-Antikörper ist ein Huhn -Antikörper zur Detektion von MBP in WB und IF. Geeignet für Human, Maus, Ratte und Rind (Kuh).

Kurzübersicht für MBP Antikörper (ABIN1110156)

Target: MBP (Myelin Basic Protein (MBP))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Huhn

Konjugat: Dieser MBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-MBP Antikörper

Aufreinigung: Aff - Purified

Immunogen: Mixture of 3 MBP peptides which are the different forms of the protein which are alternate transcription from a single gene.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Details zu MBP

Target: MBP (Myelin Basic Protein (MBP))

Andere Bezeichnung: Myelin Basic Protein

Hintergrund: Myelin basic protein is reported to account for about 30 of the proteins in myelin found in the central nervous system. It can induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity, though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Four different isoforms have been identified through cDNA cloning. All four of these variants are identical except for the insertion or deletion of two peptide fragments encoded by exons 2 and 5. Myelin basic protein is reported to be expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves, though it is expressed less abundantly in gray matter.