MBP Antikörper

Produktnummer ABIN1110155

Der Maus Monoklonal Anti-MBP-Antikörper wurde für WB und IF validiert. Er ist geeignet, MBP in Proben von Human und Ratte zu detektieren.

Kurzübersicht für MBP Antikörper (ABIN1110155)

Target: MBP (Myelin Basic Protein (MBP))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-MBP Antikörper

Aufreinigung: Ascites

Immunogen: Mixture of 3 MBP peptides which are the different forms of the protein which are alternate transcription from a single gene.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Details zu MBP

Target: MBP (Myelin Basic Protein (MBP))

Andere Bezeichnung: Myelin Basic Protein

Hintergrund: Myelin basic protein is reported to account for about 30 of the proteins in myelin found in the central nervous system. It can induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity, though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Four different isoforms have been identified through cDNA cloning. All four of these variants are identical except for the insertion or deletion of two peptide fragments encoded by exons 2 and 5. Myelin basic protein is reported to be expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves, though it is expressed less abundantly in gray matter. Image: