IKZF4 Antikörper (N-Term)
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- Target Alle IKZF4 Antikörper anzeigen
- IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IKZF4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- NSIKVEMYSD EESSRLLGPD ERLLEKDDSV IVEDSLSEPL GYCDGSGPEP
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse, Rat, Dog
- Aufreinigung
- Purified using Protein A affinity column
- Immunogen
- The immunogen for anti-ZNFN1A4 antibody: synthetic peptide directed towards the N terminal of human ZNFN1A4
- Top Product
- Discover our top product IKZF4 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Add 100 μL of distilled water to a final concentration of 1 mg/mL.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- Target
- IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
- Andere Bezeichnung
- ZNFN1A4 / IKZF4 / EOS (IKZF4 Produkte)
- Hintergrund
- IKZF4 also called ZNFN1A4 is a DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence and acts as transcriptional repressor. It interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2 and may be involved in the development of central and peripheral nervous systems. Highly expressed in skeletal muscle, low levels of expression in heart, thymus, kidney, liver, and spleen. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.Synonyms: Ikaros family zinc finger protein 4, KIAA1782, Zinc finger protein Eos
- Molekulargewicht
- 64 kDa (585 aa)
- Gen-ID
- 64375
- NCBI Accession
- NP_071910
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