Tumor Protein p73 Antikörper (C-Term)

Produktnummer ABIN1109413

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Tumor Protein p73 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Tumor Protein p73 Antikörper (C-Term) (ABIN1109413)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tumor Protein p73 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Tumor Protein p73 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Tumor protein p73 (alpha) at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Immunogen affinity purified

Immunogen: A peptide mapping at the C-terminal end of human P73a .Remarks: Sequence differs from the related rat sequence by single amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Hintergrund: P73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate p73 is markedly increased by gamma-irradiation. Moreover, p73 was phosphorylated in vivo in response to ionizing radiation. p73, a member of the p53 family of tumour-suppressor proteins, can also induce apoptosis.p73 gene is mapped to chromosome 1p36. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.Synonyms: p53-like transcription factor, p53-related protein

Gen-ID: 7161

NCBI Accession: NP_001119712

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus