Tumor Protein p73 Antikörper (C-Term)

Produktnummer ABIN1109413

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Tumor Protein p73 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Tumor Protein p73 Antikörper (C-Term) (ABIN1109413)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tumor Protein p73 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Tumor Protein p73 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Tumor protein p73 (alpha) at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Immunogen affinity purified

Immunogen: A peptide mapping at the C-terminal end of human P73a .Remarks: Sequence differs from the related rat sequence by single amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Hintergrund: P73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate p73 is markedly increased by gamma-irradiation. Moreover, p73 was phosphorylated in vivo in response to ionizing radiation. p73, a member of the p53 family of tumour-suppressor proteins, can also induce apoptosis.p73 gene is mapped to chromosome 1p36. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.Synonyms: p53-like transcription factor, p53-related protein

Gen-ID: 7161

NCBI Accession: NP_001119712

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus