TRIM13 Antikörper (Middle Region)
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- Target Alle TRIM13 Antikörper anzeigen
- TRIM13 (Tripartite Motif Containing 13 (TRIM13))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TRIM13 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Sequenz
- DTLETSKRKS LQLLTKDSDK VKEFFEKLQH TLDQKKNEIL SDFETMKLAV
- Kreuzreaktivität (Details)
- Species reactivity (expected):Rat, Mouse, BovineSpecies reactivity (tested):Human
- Aufreinigung
- Purified using peptide immunoaffinity column
- Immunogen
- The immunogen for anti-TRIIM13 antibody: synthetic peptide directed towards the middle region of human TRIM13
- Top Product
- Discover our top product TRIM13 Primärantikörper
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anti-Tripartite Motif Containing 13 (TRIM13) (Middle Region) antibody
TRIM13 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 40-310) antibodyTRIM13 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (Middle Region) antibodyTRIM13 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 1-100) antibodyTRIM13 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 165-214) antibodyTRIM13 Reaktivität: Human, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Fledermaus, Hamster, Affe, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 40-310) antibodyTRIM13 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 61-90), (N-Term) antibodyTRIM13 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB33240 unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) antibodyTRIM13 Reaktivität: Human IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 1-100) antibodyTRIM13 Reaktivität: Human ELISA Wirt: Maus Monoclonal 1E5 unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 1-100) antibodyTRIM13 Reaktivität: Human ELISA Wirt: Maus Monoclonal 2A11 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- Target
- TRIM13 (Tripartite Motif Containing 13 (TRIM13))
- Andere Bezeichnung
- TRIM13 / RNF77 (TRIM13 Produkte)
- Hintergrund
- TRIM13 is an E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. TRIM13 enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation, regulates ER stress-induced autophagy, and may act as a tumor suppressor.Synonyms: B-cell chronic lymphocytic leukemia tumor suppressor Leu5, LEU5, Leukemia-associated protein 5, Putative tumor suppressor RFP2, RFP2, RING finger protein 77, Tripartite motif-containing protein 13
- Gen-ID
- 10206
- NCBI Accession
- NP_005789
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