Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.1 M Tris, 0.1 M Glycine, 50 % Glycerol, pH 7.8, 0.02 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Target
TGM1
(Transglutaminase 1, Keratinocyte (TGM1))
Andere Bezeichnung
Transglutaminase-1 (TGM1)
Hintergrund
Tissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is one of the more common disorders in Western countries.Synonyms: Epidermal TGase, KTG, Protein-glutamine gamma-glutamyltransferase K, TGase K, Transglutaminase K