TGFB2 Antikörper (N-Term)

Produktnummer ABIN1109226

Dieses Anti-TGFB2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TGFB2 in WB, IHC (fro) und EIA. Geeignet für Human.

Kurzübersicht für TGFB2 Antikörper (N-Term) (ABIN1109226)

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGFB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Produktdetails anti-TGFB2 Antikörper

Bindungsspezifität: N-Term

Spezifität: Reacts with Human 48 kDa TGFB2 protein.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from N-terminal domain of Human TGFB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in distilled water.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer

Details zu TGFB2

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Andere Bezeichnung: TGF-beta-2 (TGFB2)

Hintergrund: Transforming growth factor beta's (TGF beta's) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFalpha. It is now realized that TGF beta's mediate many cell-cell interactions that occur during embryonic development. Three TGF beta's have been identified in mammals. TGFB1, TGFB2 and TGFB3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF beta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFB3 protein has approximately 80 % identity to the mature region of both TGFB1 and TGFB2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity.Synonyms: BSC-1 cell growth inhibitor, Cetermin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Polyergin, Transforming growth factor beta-2

Gen-ID: 7042

NCBI Accession: NP_001129071

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus