Synaptophysin Antikörper

Produktnummer ABIN1109181

Dieses Anti-Synaptophysin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Synaptophysin in WB und IHC (p). Geeignet für Human und Maus.

Kurzübersicht für Synaptophysin Antikörper (ABIN1109181)

Target: Synaptophysin (SYP)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Synaptophysin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 171B5

Produktdetails anti-Synaptophysin Antikörper

Spezifität: Reacts with human and mouse Synaptophysin.

Aufreinigung: Protein A agarose

Immunogen: Purified synaptic vesicle fraction from guinea pig cerebrum

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservtives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots) at -20 °C.

Details zu Synaptophysin

Target: Synaptophysin (SYP)

Andere Bezeichnung: Synaptophysin / SYP

Hintergrund: Synaptophysin (also referred to as SVP38 and p38) is an acidic Ca2+ binding glycoprotein of about 38 kDa which exist largely in synaptic vesicles. It has 4 transmembrane regions and is reported to be a major cholesterol-binding protein in synaptic vesicles. Synaptophysin may regulate synaptic exocytosis by competing with proteins such as SNAP25 and syntaxins to bind to synaptobrevin (vesicle-associated membrane protein, or VAMP). It may also participate in synaptic endocytosis, which contributes to rapid recycling of synaptic vesicle.Synonyms: Major synaptic vesicle protein p38, Neuroendocrine Marker

Gen-ID: 6855

NCBI Accession: NP_003170

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity