SHOX2 Antikörper (Middle Region)

Produktnummer ABIN1109006

Der Kaninchen Polyklonal Anti-SHOX2 Antikörper wurde für WB validiert. Er ist geeignet, SHOX2 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für SHOX2 Antikörper (Middle Region) (ABIN1109006)

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHOX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SHOX2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: SEARVQVWFQ NRRAKCRKQE NQLHKGVLIG AASQFEACRV APYVNVGALR

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-SHOX2 antibody: synthetic peptide directed towards the middle region of human SHOX2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu SHOX2

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Andere Bezeichnung: SHOX2 / SHOT

Hintergrund: SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.Synonyms: Homeobox protein Og12X, OG12X, Paired-related homeobox protein SHOT, Short stature homeobox protein 2

Gen-ID: 6474

NCBI Accession: NP_006875

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development