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SCD Antikörper
SCD
Reaktivität: Human, Maus
WB, IP, IHC (fro), EIA
Wirt: Maus
Monoclonal
CD-E10
unconjugated
Produktnummer ABIN1108939
Produktdetails anti-SCD Antikörper
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Target
Alle SCD Antikörper anzeigen
SCD
(Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))
Reaktivität
Alle Reaktivitäten für SCD Antikörper
Human, Maus
Wirt
Alle Wirte für SCD Antikörper
Maus
Klonalität
Alle Klonalitäten für SCD Antikörper
Monoklonal
Konjugat
Alle Konjugate für SCD Antikörper
Dieser SCD Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SCD Antikörper
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
Spezifität
This antibody reacts to SCD / SCD1.
Aufreinigung
Affinity Purified
Immunogen
Full length recombinant protein
Klon
CD-E10
Isotyp
IgG2b
Top Product
Discover our top product SCD Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1,0 mg/mL
Buffer
PBS, pH 7.4 with 0.05 % sodium azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu SCD
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Target
SCD
(Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))
Andere Bezeichnung
SCD / SCD1 (SCD Produkte )
Synonyme
FADS5 antikoerper, MSTP008 antikoerper, SCD1 antikoerper, SCDOS antikoerper, AA589638 antikoerper, AI265570 antikoerper, Scd antikoerper, Scd-1 antikoerper, ab antikoerper, SCD antikoerper, fads5 antikoerper, scd1 antikoerper, scdos antikoerper, F27J15.17 antikoerper, F27J15_17 antikoerper, STOMATAL CYTOKINESIS-DEFECTIVE 1 antikoerper, cds2 antikoerper, desaturase antikoerper, stearoyl-CoA desaturase antikoerper, acyl-CoA desaturase antikoerper, Acyl-CoA desaturase antikoerper, stearoyl-Coenzyme A desaturase 1 antikoerper, stearoyl-CoA desaturase (delta-9-desaturase) antikoerper, stearoyl-CoA desaturase (delta-9-desaturase) S homeolog antikoerper, stomatal cytokinesis defective / SCD1 protein (SCD1) antikoerper, acyl-CoA desaturase-like antikoerper, SCD antikoerper, CIMG_08158 antikoerper, VIBHAR_RS23280 antikoerper, acod antikoerper, Scd1 antikoerper, Scd antikoerper, scd antikoerper, LOC100346561 antikoerper, scd.S antikoerper, SCD1 antikoerper, LOC100719661 antikoerper, LOC101835884 antikoerper, LOC109101093 antikoerper
Hintergrund
Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa, ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders.Synonyms: Acyl-CoA desaturase, Delta(9)-desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase
Gen-ID
6319
NCBI Accession
NP_005054
UniProt
O00767
Pathways
Brown Fat Cell Differentiation
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