EXOSC2 Antikörper

Produktnummer ABIN1108908

Dieses Anti-EXOSC2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von EXOSC2 in EIA. Geeignet für Human.

Kurzübersicht für EXOSC2 Antikörper (ABIN1108908)

Target: EXOSC2 (Exosome Component 2 (EXOSC2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EXOSC2 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: 15B3

Produktdetails anti-EXOSC2 Antikörper

Spezifität: Specificity has been tested in ELISA. Additional tests for cross reactivity have not yet been performed.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: Recombinant GST-hRRP4 (NCBI accession number NM_014285 REGION 3-884, expression vector pGEX-4T3), expressed in E.coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL (when dissolved at 0.5 mg/mL, the BSA concentration will be 1%)

Buffer: 10 mM Ammonium Bicarbonate buffer, 2 mg BSA

Vorsichtsmaßnahmen: Be careful opening the vial since the antibody resides in a vacuum.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu EXOSC2

Target: EXOSC2 (Exosome Component 2 (EXOSC2))

Andere Bezeichnung: RRP4 / EXOSC2

Hintergrund: The exosome, present in both the nucleus and cytoplasm of all eukaryotic cells, is a complex of 3'-5' exoribonucleases containing at least nine core components. Recently, it has been demonstrated, mainly by analyses in yeast, that the nuclear exosome is essential for rRNA processing and sn(o)RNA biogenesis. Furthermore, it is involved in the degradation of improperly processed mRNAs. The cytoplasmic exosome participates in normal mRNA turnover and in the degradation of inherently instable mRNAs that contain AU-rich elements. Therefore, the exosome plays a key role in RNA metabolism.Synonyms: Exosome complex exonuclease RRP4, Exosome component 2, Ribosomal RNA-processing protein 4

Gen-ID: 23404

NCBI Accession: NP_055100

UniProt: Q13868

Pathways: SARS-CoV-2 Protein Interaktom