RECK Antikörper (AA 621-832)
Kurzübersicht für RECK Antikörper (AA 621-832) (ABIN1108847)
Target
Alle RECK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 621-832
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Spezifität
- This antibody reacts with RECK.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Aufreinigung
- Protein A agarose
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Immunogen
- Recombinant RECK protein (621-832 a.a)
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store (in aliquots) at -20 °C.
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- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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Andere Bezeichnung
- RECK / ST15
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Hintergrund
- A membrane-anchored glycoprotein, RECK is encoded by a RECK gene (reversion-inducing cysteine-rich protein with Kazal motifs) identified as a transformation suppressor gene. This 110 kDa protein consists of 971a.a. The protein contains protease inhibitor like domains such as the Kazal motif, and epidermal growth factor (EGF) like repeats. Takahashi et al. reported that restoration pf RECK expression in malignant cells resulted in suppression of invasive activity with a concomitant decrease in the secretion of matrix metalloproteinase-9 (MMP-9), a key enzyme involved in tumor invasion and metastasis.Synonyms: Reversion-inducing cysteine-rich protein with Kazal motifs, Suppressor of tumorigenicity 15 protein
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Gen-ID
- 8434
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NCBI Accession
- NP_066934
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UniProt
- O95980
Target
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