POU1F1 Antikörper (N-Term)

Produktnummer ABIN1108700

Der Kaninchen Polyklonal Anti-POU1F1-Antikörper wurde für WB validiert. Er ist geeignet, POU1F1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Schwein und Huhn zu detektieren.

Kurzübersicht für POU1F1 Antikörper (N-Term) (ABIN1108700)

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU1F1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-POU1F1 Antikörper

Bindungsspezifität: N-Term

Sequenz: TPCLYKFPDH TLSHGFPPIH QPLLAEDPTA ADFKQELRRK SKLVEEPIDM

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Bovine, Pig, Dog, ChickenSpecies reactivity (tested):Human

Aufreinigung: Protein A affinity column

Immunogen: The immunogen for anti-POU1F1 antibody: synthetic peptide directed towards the N terminal of human POU1F1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 100 μL of distilled water

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term

Haltbarkeit: 12 months

Details zu POU1F1

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Andere Bezeichnung: POU1F1

Hintergrund: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.Synonyms: GHF-1, GHF1, Growth hormone factor 1, PIT-1, PIT1, Pituitary-specific positive transcription factor 1

Gen-ID: 5449

NCBI Accession: NP_000297

Pathways: Regulation of Carbohydrate Metabolic Process