POU1F1 Antikörper (C-Term)

Produktnummer ABIN1108699

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch POU1F1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Schwein und Huhn.

Kurzübersicht für POU1F1 Antikörper (C-Term) (ABIN1108699)

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU1F1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-POU1F1 Antikörper

Bindungsspezifität: C-Term

Sequenz: QEIMRMAEEL NLEKEVVRVW FCNRRQREKR VKTSLNQSLF SISKEHLECR

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Bovine, Pig, ChickenSpecies reactivity (tested):Human

Aufreinigung: Purified on peptide immunoaffinity column

Immunogen: The immunogen for anti-POU1F1 antibody: synthetic peptide directed towards the C terminal of human POU1F1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Haltbarkeit: 12 months

Details zu POU1F1

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Andere Bezeichnung: POU1F1

Hintergrund: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.Synonyms: GHF-1, GHF1, Growth hormone factor 1, PIT-1, PIT1, Pituitary-specific positive transcription factor 1

Gen-ID: 5449

NCBI Accession: NP_000297

Pathways: Regulation of Carbohydrate Metabolic Process