POP7 Antikörper
Kurzübersicht für POP7 Antikörper (ABIN1108698)
Target
Alle POP7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Specificity has been tested in ELISA. In immunoblotting, under less stringent washing conditions, a weaker band of approximately 60 kDa is also detected (Figure 1, Right Panel). Additional tests for cross reactivity have not yet been performed.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Aufreinigung
- Purified
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Immunogen
- Recombinant GST-hRPP20 (NCBI accession number AAC24113, expression vector pGEC-2T), expressed in E.coli.
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Dissolve in 200 μL buffer for a 0.5 mg/mL antibody concentration in 1 % BSA
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Konzentration
- 0.5 mg/mL (when dissolved at 0.5 mg/mL, the BSA concentration will be 1%)
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Buffer
- 10 mM Ammonium Bicarbonate buffer, 2 mg BSA
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Vorsichtsmaßnahmen
- Be careful opening the vial since the antibody resides in a Vacuum.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C or Add up to 0.05% Sodium Azide for long term storage.
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- POP7 (Processing of Precursor 7, Ribonuclease P/MRP Subunit (POP7))
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Andere Bezeichnung
- POP7
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Hintergrund
- The nuclei of eukaryotic cells contain several classes of small RNA-protein complexes. SnRNPs (small nuclear ribonucleoproteins) are involved in splicing of pre-mRNAs (the excision of introns) in the nucleoplasm. RPP20 is part of such a complex. SnoRNPs (small nucleolar ribonucleoproteins) are involved in the maturation of pre-ribosomal RNA in the nucleoli. Pre-rRNA processing and modification require both the snoRNA and the protein constituents (such as Rpp20) of these complexes. Generally, snoRNPs contain a number of common proteins, which are shared with other snoRNPs of the same family, next to several particle-specific proteins. On average, snoRNPs contain about 6-10 protein subunits.Synonyms: RPP20, Ribonuclease P protein subunit p20, Ribonucleases P/MRP protein subunit POP7 homolog, hPOP7
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Molekulargewicht
- 20 kDa
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Gen-ID
- 10248
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NCBI Accession
- NP_005828
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UniProt
- O75817
Target
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