POP7 Antikörper

Produktnummer ABIN1108698

Dieses Anti-POP7-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von POP7 in WB und EIA. Geeignet für Human.

Kurzübersicht für POP7 Antikörper (ABIN1108698)

Target: POP7 (Processing of Precursor 7, Ribonuclease P/MRP Subunit (POP7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser POP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 1F11

Produktdetails anti-POP7 Antikörper

Spezifität: Specificity has been tested in ELISA. In immunoblotting, under less stringent washing conditions, a weaker band of approximately 60 kDa is also detected (Figure 1, Right Panel). Additional tests for cross reactivity have not yet been performed.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: Recombinant GST-hRPP20 (NCBI accession number AAC24113, expression vector pGEC-2T), expressed in E.coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Dissolve in 200 μL buffer for a 0.5 mg/mL antibody concentration in 1 % BSA

Konzentration: 0.5 mg/mL (when dissolved at 0.5 mg/mL, the BSA concentration will be 1%)

Buffer: 10 mM Ammonium Bicarbonate buffer, 2 mg BSA

Vorsichtsmaßnahmen: Be careful opening the vial since the antibody resides in a Vacuum.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C or Add up to 0.05% Sodium Azide for long term storage.

Details zu POP7

Target: POP7 (Processing of Precursor 7, Ribonuclease P/MRP Subunit (POP7))

Andere Bezeichnung: POP7

Hintergrund: The nuclei of eukaryotic cells contain several classes of small RNA-protein complexes. SnRNPs (small nuclear ribonucleoproteins) are involved in splicing of pre-mRNAs (the excision of introns) in the nucleoplasm. RPP20 is part of such a complex. SnoRNPs (small nucleolar ribonucleoproteins) are involved in the maturation of pre-ribosomal RNA in the nucleoli. Pre-rRNA processing and modification require both the snoRNA and the protein constituents (such as Rpp20) of these complexes. Generally, snoRNPs contain a number of common proteins, which are shared with other snoRNPs of the same family, next to several particle-specific proteins. On average, snoRNPs contain about 6-10 protein subunits.Synonyms: RPP20, Ribonuclease P protein subunit p20, Ribonucleases P/MRP protein subunit POP7 homolog, hPOP7

Molekulargewicht: 20 kDa

Gen-ID: 10248

NCBI Accession: NP_005828

UniProt: O75817