Occludin Antikörper (AA 358-504)

Produktnummer ABIN1108503

Dieses Anti-Occludin-Antikörper ist ein Meerschweinchen Polyklonal-Antikörper zur Detektion von Occludin in WB, IF und IHC (fro). Geeignet für Human, Maus, Ratte und Hund. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Occludin Antikörper (AA 358-504) (ABIN1108503)

Target: Occludin (OCLN)

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Meerschweinchen

Klonalität: Polyklonal

Konjugat: Dieser Occludin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Occludin Antikörper

Bindungsspezifität: AA 358-504

Spezifität: The polyclonal antibody reacts with Occludin.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat, Canine.

Aufreinigung: Protein A Chromatography

Immunogen: Recombinant Human Occludin (aa 358-504)

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % Sodium Azide, 0.1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C.

Referenzen für anti-Occludin Antikörper (ABIN1108503)

Liu, Gu, Zhu, Yuan, Zhu, Zhu, Yao, Hu, Zhang, Dicksved, Bao, Cai: "Epithelial Heat Shock Proteins Mediate the Protective Effects of Limosilactobacillus reuteri in Dextran Sulfate Sodium-Induced Colitis." in: Frontiers in immunology, Vol. 13, pp. 865982, (2022) (PubMed).

Details zu Occludin

Target: Occludin (OCLN)

Andere Bezeichnung: Occludin

Hintergrund: Occludin is an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1).Synonyms: OCLN

Gen-ID: 100506658

NCBI Accession: NP_001192183

UniProt: Q16625

Pathways: Cell-Cell Junction Organization, Hepatitis C