MUC5AC Antikörper

Produktnummer ABIN1108320

Produktdetails anti-MUC5AC Antikörper

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MUC5AC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: A BALB/c mouse was immunized with Mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classisfication). Splenocytes were fused with mouse myeloma SP2/0 cells.

Klon: 1-13M1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on cultured cells. Immunochemistry on Frozen Ethanol Fixed Sections. Immunochemistry on Paraffin Sections: a protease pretreatment is recommended. This antibody clone 1-13M1 cross reacts with Mucin of different animal species after period date pretreatment. Immunoblotting: Strongly positive without mercaptoethanol pretreatment of mucin solution. ELISA or IRMA in combination with the clone 9-13M1 or the mixture of anti-M1 Monoclonal antibodies.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MUC5AC

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Andere Bezeichnung: Mucin-5AC (MUC5AC Produkte)

Hintergrund: Mucins are high molecular weight glycoproteins that are found especially in the secretions of mucus membranes. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.Synonyms: Gastric mucin, LeB, Lewis B blood group antigen, MUC5, MUC5AC, Major airway glycoprotein, Mucin-5 subtype AC, TBM, Tracheobronchial mucin, tracheobronchial

Gen-ID: 9606

UniProt: P98088