Afadin Antikörper (AA 1814-1829)

Produktnummer ABIN1108256

Der Maus Monoklonal Anti-Afadin-Antikörper wurde für WB, IP und EIA validiert. Er ist geeignet, Afadin in Proben von Human, Ratte, Maus und Hund zu detektieren.

Kurzübersicht für Afadin Antikörper (AA 1814-1829) (ABIN1108256)

Target: Afadin (MLLT4)

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Afadin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Klon: 3

Produktdetails anti-Afadin Antikörper

Bindungsspezifität: AA 1814-1829

Spezifität: This antibody detects L-Afadin.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat, dog

Aufreinigung: Protein G

Immunogen: Peptide 1814-1829 aa of rat l-afadin

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu Afadin

Target: Afadin (MLLT4)

Andere Bezeichnung: MLLT4 / AF6 / Afadin

Hintergrund: Afadin is an actin filament-binding protein that is involved in cell-cell adherens junctions (AJs) which directly interacts with the alpha herpus virus receptor, a member of the immunoglobulin supergene family. Afadin is colocalized with nectin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. L-Afadin has been isolated as an F-actin-binding protein from rat brain. L-afadin is ubiquitously expressed and specifically localized at zonula adherens (ZA) in epithelial cells and at cell-cell adherens junctions (AJs) in non-epithelial cells. L-afadin has a splice variant, named small intestine absorptive afadin (s-afadin) which is abundantly expressed in neural tissue.Synonyms: Myeloid/lymphoid Or Mixed-lineage Leukemia Translocated To 4, Protein AF-6

Gen-ID: 26955

NCBI Accession: NP_037349

UniProt: O35889

Pathways: Cell-Cell Junction Organization