MIER1 Antikörper (Middle Region)

Produktnummer ABIN1108246

Produktdetails anti-MIER1 Antikörper

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIER1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Zebrafish, African clawed frog, Chicken, Bovine, RabbitSpecies reactivity (tested):Human

Aufreinigung: Purified using Protein A affinity column

Immunogen: The immunogen for anti-MIER1 antibody: synthetic peptide directed towards the middle region of human MIER1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu MIER1

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Andere Bezeichnung: MIER1 (MIER1 Produkte)

Synonyme: 4933425I22Rik antikoerper, 5830411K19Rik antikoerper, mKIAA1610 antikoerper, mier1 antikoerper, wu:fb30a02 antikoerper, zgc:56179 antikoerper, mi-er1 antikoerper, ER1 antikoerper, MI-ER1 antikoerper, RGD1562337 antikoerper, MEIR1 treanscription regulator antikoerper, MIER1 transcriptional regulator antikoerper, mesoderm induction early response 1a, transcriptional regulator antikoerper, mesoderm induction early response 1, transcriptional regulator L homeolog antikoerper, Mier1 antikoerper, MIER1 antikoerper, mier1a antikoerper, mier1.L antikoerper

Hintergrund: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).Synonyms: Early response 1, Er1, KIAA1610, Mesoderm induction early response protein 1, Mi-er1, hmi-er1

Gen-ID: 57708

NCBI Accession: NP_065999

Pathways: Chromatin Binding