MIER1 Antikörper (Middle Region)

Produktnummer ABIN1108246

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MIER1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Huhn und Xenopus laevis.

Kurzübersicht für MIER1 Antikörper (Middle Region) (ABIN1108246)

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIER1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MIER1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Zebrafish, African clawed frog, Chicken, Bovine, RabbitSpecies reactivity (tested):Human

Aufreinigung: Purified using Protein A affinity column

Immunogen: The immunogen for anti-MIER1 antibody: synthetic peptide directed towards the middle region of human MIER1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu MIER1

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Andere Bezeichnung: MIER1

Hintergrund: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).Synonyms: Early response 1, Er1, KIAA1610, Mesoderm induction early response protein 1, Mi-er1, hmi-er1

Gen-ID: 57708

NCBI Accession: NP_065999

Pathways: Chromatin Binding