Endothelin 1 Antikörper (C-Term)

Produktnummer ABIN110809

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch Endothelin 1 in RIA und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Endothelin 1 Antikörper (C-Term) (ABIN110809)

Target: Endothelin 1 (EDN1)

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Endothelin 1 Antikörper ist unkonjugiert

Applikation: Radioimmunoassay (RIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 3G10

Produktdetails anti-Endothelin 1 Antikörper

Bindungsspezifität: C-Term

Sequenz: C-H-L-D-I-I-W

Spezifität: Reacts with the C-terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin.

Aufreinigung: Protein G affinity chromatography

Immunogen: Synthetic human endothelin-C terminal fragment, conjugated to BSA

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: RIA / IRMA. Immunohistochemistry on frozen sections: Frozen sections processed with dry acetone are recommended. Paraformaldehyde is notrecommended as it destroys the epitope.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Endothelin 1

Target: Endothelin 1 (EDN1)

Andere Bezeichnung: Endothelin-1

Hintergrund: Endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.Synonyms: Big endothelin-1, EDN1, EDN2, ET-2, ET-3, Endothelin-2, Endothelin1, PPET1, PPET2, PPET3, Preproendothelin-1, Preproendothelin-2, Preproendothelin-3

Gen-ID: 1906

NCBI Accession: NP_001946

UniProt: P05305

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size