LRG1 Antikörper
Kurzübersicht für LRG1 Antikörper (ABIN1108060)
Target
Alle LRG1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The monoclonal antibody recognizes leucine-rich alpha-2-glycoprotein (LRG), a member of the leucine-rich repeat family. It can be used for immuno purification of human LRG.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Aufreinigung
- Protein G
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Immunogen
- Human LRG, covalently coupled to hemocyanin using glutaraldehyde
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C.
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- LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))
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Andere Bezeichnung
- LRG1
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Hintergrund
- LRG is a plasma protein of approximately 50 kDa. LRG consists of 312 amino acids. It has 1 galactosamine and 4 glucosamine oliogosacharides attached and has 2 intrachain disulfide bonds. Leucine comprises 66 of the 312 amino acids, and LRG contains at least eight 24-amino acid leucine-rich repeats. The consensus of these residues, termed leucine-rich repeats (LRR), has been identified as an LRR-containing domain. The primary function of LRRs is to provide versatile structural framework of the formation of protein-protein interactions. LRG is expressed during granulocyte differentiation. Although several family members of the leucine-rich repeat family have been shown to be involved in signal transduction, protein-protein interaction, or cell adhesion and development, a function for LRG remains elusive. LRG has been reported as a biomarker for certain diseases including microbial infections and cancer. LRG can be detected in human neutrophils and progenitor cells, but not in peripheral blood mononuclear cells.Synonyms: LRG, Leucine-rich alpha-2-glycoprotein
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Gen-ID
- 116844
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NCBI Accession
- NP_443204
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UniProt
- P02750
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Pathways
- Brown Fat Cell Differentiation
Target
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