LRG1 Antikörper

Produktnummer ABIN1108060

Dieses Maus Monoklonal-Antikörper erkennt spezifisch LRG1 in EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LRG1 Antikörper (ABIN1108060)

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LRG1 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: 2F5-A2

Produktdetails anti-LRG1 Antikörper

Spezifität: The monoclonal antibody recognizes leucine-rich alpha-2-glycoprotein (LRG), a member of the leucine-rich repeat family. It can be used for immuno purification of human LRG.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein G

Immunogen: Human LRG, covalently coupled to hemocyanin using glutaraldehyde

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu LRG1

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Andere Bezeichnung: LRG1

Hintergrund: LRG is a plasma protein of approximately 50 kDa. LRG consists of 312 amino acids. It has 1 galactosamine and 4 glucosamine oliogosacharides attached and has 2 intrachain disulfide bonds. Leucine comprises 66 of the 312 amino acids, and LRG contains at least eight 24-amino acid leucine-rich repeats. The consensus of these residues, termed leucine-rich repeats (LRR), has been identified as an LRR-containing domain. The primary function of LRRs is to provide versatile structural framework of the formation of protein-protein interactions. LRG is expressed during granulocyte differentiation. Although several family members of the leucine-rich repeat family have been shown to be involved in signal transduction, protein-protein interaction, or cell adhesion and development, a function for LRG remains elusive. LRG has been reported as a biomarker for certain diseases including microbial infections and cancer. LRG can be detected in human neutrophils and progenitor cells, but not in peripheral blood mononuclear cells.Synonyms: LRG, Leucine-rich alpha-2-glycoprotein

Gen-ID: 116844

NCBI Accession: NP_443204

UniProt: P02750

Pathways: Brown Fat Cell Differentiation