Lipase A Antikörper

Produktnummer ABIN1108046

Produktdetails anti-Lipase A Antikörper

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Lipase A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to LAL.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Klon: 9G7F12

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0,03 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu Lipase A

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Andere Bezeichnung: LIPA (LIPA Produkte)

Synonyme: cesd antikoerper, lal antikoerper, LIPA antikoerper, CESD antikoerper, LAL antikoerper, Chole antikoerper, Chole2 antikoerper, Lip1 antikoerper, AA960673 antikoerper, Lal antikoerper, Lip-1 antikoerper, lipase A, lysosomal acid type antikoerper, lipase A, lysosomal acid, cholesterol esterase antikoerper, lipase A, lysosomal acid, cholesterol esterase L homeolog antikoerper, lysosomal acid lipase A antikoerper, LIPA antikoerper, lipa antikoerper, lipa.L antikoerper, Lipa antikoerper

Hintergrund: Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.Synonyms: Acid cholesteryl ester hydrolase, Cholesteryl esterase, EC=3.1.1.13, LAL, LIPA, Lipase A, Lysosomal acid lipase/cholesteryl ester hydrolase, Sterol esterase

Gen-ID: 3988