Lactoferrin Antikörper

Produktnummer ABIN1107998

Der Kaninchen Polyklonal anti-Lactoferrin Antikörper wird verwendet zum Nachweis von Lactoferrin in Proben von Rind (Kuh). Er wurde validiert für WB, IP und EIA.

Kurzübersicht für Lactoferrin Antikörper (ABIN1107998)

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Reaktivität: Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lactoferrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Produktdetails anti-Lactoferrin Antikörper

Spezifität: This antibody detects Bovine Lactoferrin. Other species not tested.

Aufreinigung: Protein A Chromatography

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % Sodium Azide, 0.1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C.

Details zu Lactoferrin

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Andere Bezeichnung: Lactotransferrin

Hintergrund: Lactoferrin is an approximately 80 kDa glycoprotein which was first isolated from milk and found in epithelia and most body fluids and secretions. Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation. Lactoferrin is able to strongly bind to iron and considered to have antibacterial properties. Human lactoferrin binds to bacterial products through its highly positively charged N terminus and kills various bacteria most probably by inducing intracellular changes in these bacteria without affecting the membrane permeability. Lactoferrin also plays a role in signal transduction, immunomodulation and has antiadhesive, anticancer, antiviral activity.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

Gen-ID: 280846

NCBI Accession: NP_851341

UniProt: P24627

Pathways: Transition Metal Ion Homeostasis