Lactoferrin Antikörper

Produktnummer ABIN1107996

Dieses Anti-Lactoferrin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Lactoferrin in WB und EIA. Geeignet für Rind (Kuh). Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Lactoferrin Antikörper (ABIN1107996)

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Reaktivität: Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Lactoferrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 5F12-1-2

Produktdetails anti-Lactoferrin Antikörper

Aufreinigung: Protein G purified

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Referenzen für anti-Lactoferrin Antikörper (ABIN1107996)

Shimazaki, Kamio, Nam, Harakawa, Tanaka, Omata, Saito, Kumura, Mikawa, Igarashi, Suzuki: "Structural and immunochemical studies on bovine lactoferrin fragments." in: Advances in experimental medicine and biology, Vol. 443, pp. 41-8, (1998) (PubMed).

Shimazaki, Nam, Harakawa, Tanaka, Omata, Saito, Kumura, Mikawa, Igarashi, Suzuki: "Monoclonal antibody against bovine Lactoferricin and its epitopic site." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 58, Issue 12, pp. 1227-9, (1997) (PubMed).

Details zu Lactoferrin

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Andere Bezeichnung: Lactotransferrin

Hintergrund: Lactoferricin B is derived by enzymatic cleavage of lactoferrin which is a member of the transferrin family of metal-binding proteins found in milk and other secretory fluids and also in blood. Cleavage by pepsin of bovine lactoferrin leads to the release of Lactoferricin B (aminoacid 17-41). This peptide is highly basic, possessing five Arg (R) and three Lys (K) residues. In addition, a number of Trp (W) and Phe (F) aromatic residues are present. The two Cys (C) residues from lactoferricin B form a disulfide bond, generating an almost completely cyclical peptide. Nevertheless, the disulfide bond is not required for the antimicrobial potency. Several studies have shown that Lactoferricin B has a broad-spectrum activity against various Gram-positive and Gram-negative bacteria. In addition the peptide has been shown to have antifungal, antiviral and antitumour activity and to bind lipopolysaccharides (LPS, endotoxin). Moreover, it is known to stimulate the adaptive immune response and has anti-inflammatory properties. Lactoferricin B belongs to a large group of cationic antimicrobial peptides.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

Gen-ID: 9913

UniProt: P24627

Pathways: Transition Metal Ion Homeostasis