Histone H1 Antikörper

Produktnummer ABIN1107537

Dieser Anti-Histone H1 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von Histone H1 in IF, WB, IHC (p), IP, IHC (fro) und EIA. Geeignet für Human. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für Histone H1 Antikörper (ABIN1107537)

Target: Histone H1

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Histone H1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: AE-4

Produktdetails anti-Histone H1 Antikörper

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: A BALB/c mouse was immunized with Human leukemia biopsy cells. The isolated splenocytes were fused with mouse myeloma cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or -20 °C for longer.

Referenzen für anti-Histone H1 Antikörper (ABIN1107537)

Schlegel, Meir, Heupel, Holthöfer, Leube, Waschke: "Desmoglein 2-mediated adhesion is required for intestinal epithelial barrier integrity." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 298, Issue 5, pp. G774-83, (2010) (PubMed).

Poschmann, Sitek, Sipos, Ulrich, Wiese, Stephan, Warscheid, Klöppel, Vander Borght, Ramaekers, Meyer, Stühler: "Identification of proteomic differences between squamous cell carcinoma of the lung and bronchial epithelium." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 5, pp. 1105-16, (2009) (PubMed).

Straub, Stoeffel, Heid, Zimbelmann, Schirmacher: "Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis." in: Hepatology (Baltimore, Md.), Vol. 47, Issue 6, pp. 1936-46, (2008) (PubMed).

Andersson, Karlsson, Carlsson, Pütsep: "Expression of granule-associated proteins in neutrophils from patients with severe congenital neutropenia." in: Blood, Vol. 110, Issue 7, pp. 2772-3; author reply 2773-4, (2007) (PubMed).

Details zu Histone H1

Target: Histone H1

Hintergrund: The histone proteins serve as a structural scaffold for the organisation of nuclear DNA into chromatin. In eucariotic cells there are 4 core histone proteins, H2A, H2B, H3 and H4 that asseble to form an octamer round which the DNA is wrapped in a sequence dependant manner. The resulting complex is known as a nucleosome and is the basic subunit of chromatin. Histone H1 acts as a linker and binds to each nucleosome, and by self affinity, links these nucleosomes together resulting in the 30 nm chromatin fiber.Synonyms: H1 Histone Family, H1F4, H1F5, Histone H1a, Histone H1b