CMV Glycoprotein B (CMV gB) Antikörper

Produktnummer ABIN110746

Dieses Maus Monoklonal-Antikörper erkennt spezifisch in IF, IHC (fro), EIA und Neut. Er zeigt eine Reaktivität gegenüber Cytomegalovirus (CMV).

Kurzübersicht für CMV Glycoprotein B (CMV gB) Antikörper (ABIN110746)

Target: CMV Glycoprotein B (CMV gB)

Reaktivität: Cytomegalovirus (CMV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Neutralization (Neut)

Klon: HCMV37

Produktdetails

Spezifität: The antibody is specific for Cytomegalovirus glycoprotein B late neutralizing antigen. Reacts with MRC-5 infected cells but not uninfected cells. This antibody has been found to be Neutralizing.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Human CMV extracts.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunofluorescence. Reactive only in acetone fixed CMV infected cells or frozen sections. ELISA. Immunohistochemistry on frozen sections. Neutralization.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C DO NOT FREEZE!

Antigendetails

Target: CMV Glycoprotein B (CMV gB)

Substanzklasse: Viral Protein

Hintergrund: Human Cytomegalovirus (HCMV) glycoprotein B (gB) is an abundant virion envelope protein that has been shown to be essential for the infectivity of HCMV. HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of virus neutralizing antibodies are directed at gB. Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for CMV mediated membrane fusion along with the gH/gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, wit a MW of approximately 100 kDa.Synonyms: Cytomegalovirus, Glycoprotein B, HCMV, HHV5, UL55

Gen-ID: 1487750

NCBI Accession: NP_039989

UniProt: P06473