Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore in distilled water.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
DPYSL3
(Dihydropyrimidinase-Like 3 (DPYSL3))
Andere Bezeichnung
DPYSL3 / CRMP4
Hintergrund
The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.Synonyms: CRMP-4, Collapsin response mediator protein 4, DRP-3, DRP3, Dihydropyrimidinase-related protein 3, TUC-4, ULIP, ULIP-1, ULIP1, Unc-33-like phosphoprotein 1