Desmin Antikörper

Produktnummer ABIN1106975

Der Maus Monoklonal Anti-Desmin-Antikörper wurde für WB, IF und IHC (fro) validiert. Er ist geeignet, Desmin in Proben von Human, Ratte, Maus, Huhn, Hamster, Schwein, Hund, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für Desmin Antikörper (ABIN1106975)

Target: Desmin (DES)

Reaktivität: Human, Ratte, Maus, Huhn, Hamster, Schwein, Hund, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Desmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: RD301

Produktdetails anti-Desmin Antikörper

Aufreinigung: Purified

Immunogen: Cytoskeletal desmin extract of chicken gizzard.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS with 0.09 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the lyophilized antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. store the reconstituted antibody at -20 °C.

Details zu Desmin

Target: Desmin (DES)

Andere Bezeichnung: Desmin

Hintergrund: Desmin (53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.Synonyms: DES

Gen-ID: 9031

UniProt: P02542