Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CXCR4 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-CXCR4-Antikörper wurde für WB, IF, IHC (p) und EIA validiert. Er ist geeignet, CXCR4 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN1106858

Kurzübersicht für CXCR4 Antikörper (C-Term) (ABIN1106858)

Target

Alle CXCR4 Antikörper anzeigen
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reaktivität

  • 163
  • 90
  • 65
  • 21
  • 11
  • 10
  • 10
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 133
  • 36
  • 12
  • 9
  • 2
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 140
  • 53
  • 1
Polyklonal

Konjugat

  • 117
  • 9
  • 8
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CXCR4 Antikörper ist unkonjugiert

Applikation

  • 128
  • 66
  • 56
  • 53
  • 35
  • 29
  • 26
  • 25
  • 25
  • 25
  • 9
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 16
    • 15
    • 15
    • 12
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    This antibody detects endogenous levels of total CXCR4 protein.

    Kreuzreaktivität (Details)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    Aufreinigung

    Immunoaffinity Chromatography

    Immunogen

    Synthetic peptide from Human CXCR4. Epitope: C-Terminus

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 50 % Glycerol, 0.02 % Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    Andere Bezeichnung

    CD184 / CXCR4

    Hintergrund

    CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF1 receptor, Stromal cell-derived factor 1 receptor

    Gen-ID

    7852

    NCBI Accession

    NP_001008540

    Pathways

    Regulation of Cell Size, CXCR4-mediated Signaling Events
Sie sind hier:
Chat with us!