Chips (C-Term) Antikörper

Produktnummer ABIN1106678

Produktdetails

Target: Chips

Bindungsspezifität: C-Term

Reaktivität: Säugetier

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects with the C-terminus of CHIPS.

Aufreinigung: Protein G purified

Klon: JCC1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.01 % sodium azide, 0.1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 2-8 °C. Under recommended storage conditions, product is stable for one year.

Haltbarkeit: 12 months

Antigendetails

Target: Chips

Hintergrund: The bacterial pathogen Staphylococcus aureus is insensitive to antimicrobial host defense peptides such as defensins, protegrins, platelet microbicidal proteins and bacteriocins. Staphylococci have developed various resistance mechanisms including those specific for bacteriocins and several host defense peptides. A protein belonging to the resistance mechanism of Staphylococcus aureus is known as CHIPS (Chemotaxis Inhibiting Protein of Staphylococcus aureus). CHIPS is a protein produced by Staphylococcus aureus that inhibits chemotaxis of neutrophils by blocking the Formyl Peptide Receptor (FPR) and C5a Receptor on neutrophils. CHIPS and antibodies against CHIPS can be useful for various experimental infection models of Staphylococcus aureus. Furthermore these reagents can be of help in studies on the role of FPR and C5a in inflammatory processes.

Gen-ID: 2861356

NCBI Accession: YP_041409

UniProt: Q6GFB3