CEBPD Antikörper (N-Term)

Produktnummer ABIN1106666

Der Kaninchen Polyklonal anti-CEBPD Antikörper wird verwendet zum Nachweis von CEBPD in Proben von Human und Maus. Er wurde validiert für WB, IP und EIA.

Kurzübersicht für CEBPD Antikörper (N-Term) (ABIN1106666)

Target: CEBPD (CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEBPD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Produktdetails anti-CEBPD Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody is specific for C/EBP delta protein. No cross-reactivity is observed with Mouse C/EBPalpha or C/EBPbeta.

Kreuzreaktivität (Details): Species reactivity (expected):Human.
Species reactivity (tested):Mouse.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Recombinant protein corresponding to the amino terminus of Mouse C/EBP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.83 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu CEBPD

Target: CEBPD (CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD))

Andere Bezeichnung: CEBPD

Hintergrund: C/EBP proteins are DNA-binding proteins that are important transcriptional activators in the regulation of genes involved in immune and inflammatory responses and may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Members of the C/EBP transcription factor family are related by a high degree of amino acid sequence identity to the basic leucine zipper DNA-binding domain and show distinct but overlapping patterns of tissue- and stage-restricted expression. Osada et al. identified the consensus binding site for the family as RTTGCGYAAY (R = A or G, and Y = C or T). Phosphorylation of C/EBPdelta may increase binding activity, whereas phosphorylation of the alpha and beta family members may decrease binding affinity. C/EBPdelta is a nuclear protein that binds DNA as a dimer and can form stable heterodimers with all other C/EBP family members.Synonyms: C/EBP delta, CCAAT/enhancer-binding protein delta, NF-IL6-beta, Nuclear factor NF-IL6-beta

Gen-ID: 12609

NCBI Accession: NP_031705

UniProt: Q00322