CD8 Antikörper (PE)

Produktnummer ABIN1106578

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD8 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD8 Antikörper (PE) (ABIN1106578)

Target: CD8

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD8 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: MCD8

Produktdetails anti-CD8 Antikörper (PE)

Spezifität: The antibody detects the CD8 Molecule, expressed as a heterodimer of CD8a (32-34 kDa)and CD8b (32-34 kDa) glycoproteins. Clone MCD8 is commonly used in routine immunophenotyping, the determination of CD4/CD8 ratios in HIV/AIDS patients and aids in the identification of T cell leukemias (common T-ALL or mature T-ALL)s. MCD8 also distinguishes between chronic B and T cell lymphoid leukemias. Testing by flow cytometry using a 'lyse-wash' method on whole blood from healthy donors showed the following values expressed in terms of % of the total lymphocyte count: Product code: AM39011RP-N (anti-CD8 PE) n: 10 Mean % positive: 31,53 S.D.: 4,58 % CV: 14,52

Aufreinigung: Affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.

Details zu CD8

Target: CD8

Andere Bezeichnung: CD8

Hintergrund: CD8 acts as a co-receptor with the TcR in recognizing antigens presented by MHC Class I and plays a role in the T cell-mediated immune response. The CD8 antigen is present on most tymocytes, T cytotoxic/suppressor cells and a subpopulation of NK cells.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

Gen-ID: 925

NCBI Accession: NP_001139345

UniProt: P01732