P-Selectin Antikörper (FITC)

Produktnummer ABIN1106514

Der FITC-konjugierte Maus Monoklonal anti-P-Selectin Antikörper (Klon AK-6) (ABIN1106514) detektiert spezifisch P-Selectin in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Affe.

Kurzübersicht für P-Selectin Antikörper (FITC) (ABIN1106514)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser P-Selectin Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: AK-6

Produktdetails anti-P-Selectin Antikörper (FITC)

Spezifität: This antibody reacts with a 140 kDa antigen expressed on activated platelets and also on endothelial cells both of blood and lymph vessels.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Rhesus Monkey.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Human platelet membrane glycoproteins.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Andere Bezeichnung: CD62P / P-Selectin

Hintergrund: CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

Gen-ID: 6403

NCBI Accession: NP_002996

UniProt: P16109