CD4 Antikörper (APC)
Kurzübersicht für CD4 Antikörper (APC) (ABIN1106345)
Target
Alle CD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Anti CD4 (Edu-2) recognizes the CD4 antigen (a 55 kDa glycoprotein). Testing by flow cytometry using a 'lyse-wash'method on whole blood from healthy donors showed the following values expressed in terms of % of the total lymphocyte count: Product code: AM39008AC-N (anti-CD4 APC) Mean % positive: 46,10 S.D.:5,08 % CV: 11,03
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Aufreinigung
- Affinity chromatography
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.
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- CD4
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Andere Bezeichnung
- CD4
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Hintergrund
- CD4 plays a role in the recognition of foreign antigens presented to T cells by MHC class II molecules. Furthermore, this antigen acts as a receptor for HIV-1 by binding the viral protein gp120. The CD4 antigen is present on most thymocytes and a subpopulation of peripheral blood T cells, called T helper cells (Th). In addition, CD4 is expressed on monocytes and weak on macrophages.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
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Gen-ID
- 920
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NCBI Accession
- NP_000607
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UniProt
- P01730
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Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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