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CD4 Antikörper

CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal 4H5 unconjugated
Produktnummer ABIN1106337
  • Target Alle CD4 Antikörper anzeigen
    CD4
    Reaktivität
    • 360
    • 232
    • 128
    • 48
    • 24
    • 22
    • 20
    • 19
    • 17
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 386
    • 147
    • 137
    • 3
    • 3
    • 1
    Maus
    Klonalität
    • 531
    • 138
    • 5
    Monoklonal
    Konjugat
    • 213
    • 73
    • 65
    • 49
    • 37
    • 16
    • 13
    • 12
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CD4 Antikörper ist unkonjugiert
    Applikation
    • 538
    • 203
    • 141
    • 118
    • 98
    • 76
    • 73
    • 42
    • 39
    • 36
    • 31
    • 30
    • 17
    • 10
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody reacts with CD4 antigen.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Protein A agarose
    Immunogen
    PHA-activated human CD4+ T-cells
    Klon
    4H5
    Isotyp
    IgG1
    Top Product
    Discover our top product CD4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store (in aliquots) at -20 °C.
  • Target
    CD4
    Andere Bezeichnung
    CD4 (CD4 Produkte)
    Hintergrund
    The T cell receptor for antigen (TCR) is a membrane-bound member of the immunoglobulin superfamily (IgSF) that recognizes a complex of antigen bound to self major histocompatibility complex (MHC) molecules expressed on the cell-surface of antigen-presenting cells (APC). Both cytotoxic and helper T cells typically respond to antigen which is associated with different types of MHC molecules, class I and II, respectively. CD4 is a 55-60 kDa cell-surface glycoprotein, which participates in the molecular complexes involved both in T cell development and its antigen recognizing activity, by binding to the nonpolymorphic region of class II MHC. This interaction results in increased intercellular adhesion and enhanced stimulation of T cells by signal transduction which is mediated by intracellular molecules. CD4 is also considered as a stage marker of T cell development in thymus, for it is expressed on the cell surface in a stage specific manner, during T cell development.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
    Gen-ID
    920
    NCBI Accession
    NP_000607
    UniProt
    P01730
    Pathways
    T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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