CD37 Antikörper

Produktnummer ABIN1106328

Der Maus Monoklonal anti-CD37 Antikörper (Klon IPO-24) (ABIN1106328) detektiert spezifisch CD37 in IHC (p), IHC (fro) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CD37 Antikörper (ABIN1106328)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD37 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: IPO-24

Produktdetails anti-CD37 Antikörper

Spezifität: This antibody reacts with CD37 antigen (Human), 40-52 kDa glycoprotein. IPO-24 reacts with Human B cell lines Daudi, Raji, Namalva, Ramos and CABIL, whereas T cell lines CEM, Molt-4, Jurkat, MT-4, H9 and non-lymphoid cell lines MeWo and A-431 are not labelled. IPO-24 stains B cell follicles and the most strongly labelled elements are mantle zone lymphoid cells. Neutrofils, macrophages, thymocytes and dendritic reticulum cells are negative.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: IPO-24 was generated after immunization of BALB/c mice with spleen cells of a patient with hairy cell leukemia. Mice splenocytes were fused with the P3-X63-Ag8.653 mouse myeloma cell line.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Andere Bezeichnung: CD37

Hintergrund: CD37 is a membrane protein of the tetraspanin superfamily, which includes CD9, CD53, CD81, and the R2 antigen among others. Many of these molecules are expressed on leukocytes and have been implicated in signal transduction, cell to cell interactions, and cellular activation and development. The antigen CD37 defined by IPO-24 is B lineage restricted and is strongly expressed throughout B cell ontogeny from pre-B cells untill the plasmoblasts. CD37 is an extensively glycosylated molecule and usually two and sometimes three N-linked carbohydrate chain are attached to the protein. Synonyms: Leukocyte antigen CD37, TSPAN26, Tetraspanin-26

Gen-ID: 951

NCBI Accession: NP_001765

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response