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DC-SIGN/CD209 Antikörper

CD209 Reaktivität: Human FACS, IF Wirt: Maus Monoclonal UW60-1 unconjugated

Produktnummer ABIN1106050

Datenblatt (PDF)

Target Alle DC-SIGN/CD209 (CD209) Antikörper anzeigen

DC-SIGN/CD209 (CD209) (CD209)
Reaktivität
105

27

22

1

1
Human
Wirt
71

47

4

1
Maus
Passende Sekundärantikörper
Klonalität
70

53
Monoklonal
Konjugat
60

10

9

6

5

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert
Applikation
70

52

34

30

26

13

8

8

7

3

3

3

2

2

2

1

1
Flow Cytometry (FACS), Immunofluorescence (IF)

Spezifität

The mouse monoclonal antibody UW60.1 recognizes CD209 (DC-SIGN), a 44 kDa transmembrane receptor expressed on the surface of dendritic cells and macrophages.

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Aufreinigung

Protein-A affinity chromatography

Reinheit

> 95 % pure (by SDS-PAGE)

Immunogen

CD209-His-tagged fusion protein

Klon

UW60-1

Isotyp

IgG1

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CD209 Reaktivität: Maus WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD209 (CD209) antibody
CD209 Reaktivität: Human FACS, IHC, ICC Wirt: Maus Monoclonal UW60-1 unconjugated

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

PBS, approx. pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Target

DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung

CD209 / DC-SIGN (CD209 Produkte)

Hintergrund

CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

Gen-ID

9606

UniProt

Q9NNX6