CD1a Antikörper (FITC)
Kurzübersicht für CD1a Antikörper (FITC) (ABIN1106008)
Target
Alle CD1a Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody recognizes the largest (49 kDa) of the three variants of the CD1 heavy chain, designated as CD1a. The 49 kDa polypeptide is associated with b2-microglobulin on human cortical thymocytes, dendritic cells and Langerhans' cells. It may also be expressed on some T cell leukemias and lymphoma. The antibody does not react with peripheral blood T and B lymphocytes, monocytes, normal bone marrow mononuclear cells or normal tonsillar T and B lymphocytes.
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Aufreinigung
- Affinity chromatography
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.
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- CD1a
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Andere Bezeichnung
- CD1a
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Hintergrund
- CD1a antigen is expressed on human cortical thymocytes, dendritic cells in peripheral lymph nodes and Langerhans' cells in normal, dysplastic and neoplastic tissue. CD1 has a domain organisation similar to that of MHC Class I and its expression is inversely correlated with that of TCR and MHC Class I.Synonyms: T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6/Leu-6, hTa1, hTa1 thymocyte antigen
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Gen-ID
- 909
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NCBI Accession
- NP_001754
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UniProt
- P06126
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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