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CCR3 Antikörper

CCR3 Reaktivität: Human FACS Wirt: Maus Monoclonal 444-11 unconjugated
Produktnummer ABIN1105989
  • Target Alle CCR3 Antikörper anzeigen
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    Reaktivität
    • 80
    • 34
    • 24
    • 4
    Human
    Wirt
    • 54
    • 19
    • 8
    • 6
    Maus
    Klonalität
    • 58
    • 28
    • 1
    Monoklonal
    Konjugat
    • 41
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCR3 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 33
    • 27
    • 24
    • 16
    • 13
    • 13
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody reacts with CD193. The antibody has also been reported to inhibit chemotactic migration of monocyte-derived DCs to RANTES (Ref.4). It suppresses the capacity of monocyte-derived DCs to stimulate allogenetic TCs proliferation and TCs derived IFN-γ secretion (Ref.4).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Protein A agarose
    Immunogen
    Human CCR3 expressing transfectant (mouse pre-B cell lymphoma B300-19)
    Klon
    444-11
    Isotyp
    IgG1
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store (in aliquots) at -20 °C.
  • Target
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    Andere Bezeichnung
    CD193 / CCR3 (CCR3 Produkte)
    Synonyme
    CC-CKR-3 antikoerper, CD193 antikoerper, CKR3 antikoerper, CMKBR3 antikoerper, CC-CKR3 antikoerper, Cmkbr1l2 antikoerper, Cmkbr3 antikoerper, C-C motif chemokine receptor 3 antikoerper, chemokine (C-C motif) receptor 3 antikoerper, CCR3 antikoerper, Ccr3 antikoerper
    Hintergrund
    Dendritic cells (DCs) are major antigen presenting cells (APCs) capable of stimulation resting T cells (TCs) in the primary immune response and are more potent APCs than peripheral blood monocytes or B cells. Several CC and CXC chemokines receptors were found to be expressed on some DCs and these molecules have been implicated to mediate in part the trafficking of DCs from blood to tissues and then to lymph nodes, where they form a close association with TCs in the process of antigen presentation. Recent studies have shown that CD191/CCR1 and CD193/CCR3 are potentially involved in antigen-presenting cell function of human DCs.Synonyms: C-C CKR-3, C-C chemokine receptor type 3, CC-CKR-3, CCR-3, CKR3, CMKBR3, Eosinophil eotaxin receptor
    Gen-ID
    1232
    NCBI Accession
    NP_001828
    UniProt
    P51677
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