CX3CR1 Antikörper

Produktnummer ABIN110594

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-CX3CR1 Antikörper wird verwendet zum Nachweis von CX3CR1 in Proben von Human. Er wurde validiert für WB, FACS und IHC.

Kurzübersicht für CX3CR1 Antikörper (ABIN110594)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CX3CR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Produktdetails anti-CX3CR1 Antikörper

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Lagerung: 4 °C

Referenzen für anti-CX3CR1 Antikörper (ABIN110594)

Szukiewicz, Kochanowski, Mittal, Pyzlak, Szewczyk, Cendrowski: "CX3CL1 (fractalkine) and TNFα production by perfused human placental lobules under normoxic and hypoxic conditions in vitro: the importance of CX3CR1 signaling." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 63, Issue 3, pp. 179-89, (2014) (PubMed).

Held-Feindt, Hattermann, Mueerkoester, Wedderkopp, Knerlich-Lukoschus, Ungefroren, Mehdorn, Mentlein: "CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs)." in: Experimental cell research, (2010) (PubMed).

Details zu CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Andere Bezeichnung: CX3CR1 (V28, Fractalkine Receptor)

Hintergrund: Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine1. Human CX3CR1, also named V28, was first cloned from human genomic DNA libraries2. A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor3 ,4. Human CX3CR1 has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.

Pathways: Cellular Response to Molecule of Bacterial Origin