CHAF1B Antikörper

Produktnummer ABIN1105633

Dieser Maus Monoklonal Antikörper erkennt spezifisch CHAF1B in WB, IF und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CHAF1B Antikörper (ABIN1105633)

Target: CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CHAF1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: P60-24

Produktdetails anti-CHAF1B Antikörper

Spezifität: This antibody reacts with 60 kDa membrane protein CAF-1 on Immunoprecipitation and Immunocytochemistry.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein-A Sepharose Chromatography of hybridoma supernatant.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Konservierungsmittel: Without preservative

Details zu CHAF1B

Target: CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))

Andere Bezeichnung: CAF-1 Subunit B

Hintergrund: Chromatin assembly factor-1 (CAF-1) is a highly conserved member of the histone chaperone family that promotes chromatin assembly during DNA replication in eukaryotes. CAF-1 acts as a specialized assembly factor to target newly synthesized histones to replicating DNA. CAF-1 consists of a complex of three subunits of 150 kDa (p150), 60 kDa (p60), and 48 kDa (p48). The histone chaperone Asf1 (anti-silencing function 1) protein can interact directly with the p60 subunit of CAF-1, possibly linking CAF-1 activity to DNA repair. CAF-1 may also play a regulatory role in DNA damage processing and checkpoint control.Synonyms: CAF1A, CAF1P60, CHAF1B, Chromatin assembly factor 1 subunit B, Chromatin assembly factor I p60 subunit, M-phase phosphoprotein 7, MPHOSPH7, MPP7

Gen-ID: 8208