CDH23 Antikörper (N-Term)

Produktnummer ABIN1105632

Dieses Anti-CDH23-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CDH23 in IF, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CDH23 Antikörper (N-Term) (ABIN1105632)

Target: CDH23 (Cadherin 23 (CDH23))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDH23 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CDH23 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects endogenous levels of total CDH23 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from Human CDH23. Epitope: N-Terminus

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 50 % Glycerol, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CDH23

Target: CDH23 (Cadherin 23 (CDH23))

Andere Bezeichnung: Cadherin-23

Hintergrund: Cadherin like 23 (or Cadherin 23) is, like other members of the cadherin family, a calcium-dependent cell adhesion glycoprotein that preferentially interacts with itself in connecting cells. It is a single pass type I membrane protein that contains 27 cadherin domains. Cadherin like 23 is expressed in the neurosensory epithelium, where it is thought to be involved in stereocilia organisation and hair bundle formation. Defects in the gene encoding Cadherin like 23 are a cause of Usher syndrome, which is characterised by profound congenital sensorineural deafness and eventual blindness. Mutations in this gene are also a cause of non-syndromic sensorineural deafness autosomal recessive type 12 (DFNB12). Cadherin like 23 has also been associated with age-related hearing loss.Synonyms: CDH23, KIAA1774, KIAA1812

Gen-ID: 64072

NCBI Accession: NP_001165401

Pathways: Sensory Perception of Sound